Blar i forfatter "Akkøk, Cigdem Ahaein"

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    • Fetal and neonatal alloimmune thrombocytopenia - The Norwegian management model 

      Tiller, Heidi; Ahlen, Maria Therese; Akkøk, Cigdem Ahaein; Husebekk, Anne (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-31)
      In Norway, the management strategy for fetal and neonatal alloimmune thrombocytopenia (FNAIT) has for more than two decades differed from most other countries. The focus of this paper is to describe and discuss the Norwegian FNAIT management program. We recommend antenatal IVIg to women who previously have had a child with FNAIT-induced ICH, and usually not to HPA-1a alloimmunized pregnant women ...

    • One-year protocol biopsies from ABO-incompatible renal allografts compared with a matched cohort of ABO-compatible allografts 

      Dörje, Christina; Mjøen, Geir; Strøm, Erik Heyerdahl; Holdaas, Hallvard; Jenssen, Trond Geir; Øyen, Ole; Akkøk, Cigdem Ahaein; Småstuen, Milada C; Midtvedt, Karsten; Reisæter, Anna Varberg (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-01-21)
      Abstract: Introduction: Early acute antibody-mediated rejection (ABMR) occurs more frequently in ABO-incompatible (ABOi) than in ABO-compatible (ABOc) kidney transplantation. This could lead to increased inflammation/scarring in the ABOi grafts. Protocol biopsy data in ABOi kidney recipients are scarce.<p> <p>Methods: A single-center retrospective matched cohort study was conducted. Eighty ...

    • Strategies to develop a prophylaxis for the prevention of HPA-1a immunization and fetal and neonatal alloimmune thrombocytopenia 

      Kjær, Mette; Geisen, Christof; Akkøk, Cigdem Ahaein; Wikman, Agneta; Sachs, Ulrich; Bussel, James B.; Nielsen, Kaspar; Walles, Katarina; Curtis, Brian R.; Vidarsson, Gestur; Järås, Kerstin; Skogen, Bjørn (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-31)
      Anti-HPA-1a-antibodies are the main cause of fetal and neonatal alloimmune thrombocytopenia (FNAIT) which may result in intracranial hemorrhage (ICH) and death among fetuses and newborns. Advances in understanding the pathogenesis of FNAIT and proof of concept for prophylaxis to prevent immunization suggest that development of hyperimmune anti-HPA-1a IgG aimed at preventing immunization against ...

    • Vaccine associated benign headache and cutaneous hemorrhage after ChAdOx1 nCoV-19 vaccine: A cohort study 

      Schultz, Nina Haagenrud; Søraas, Arne Vasli; Sørvoll, Ingvild Hausberg; Akkøk, Cigdem Ahaein; Vetlesen, Annette; Bhamra, Jagjit Singh; Ahlen, Maria Therese; Holme, Pål Andre; Aamodt, Anne Hege; Skagen, Karolina Ryeng; Skattør, Thor Håkon; Skjelland, Mona; Wiedmann, Markus (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-17)
      Objectives Fatal complications have occurred after vaccination with ChAdOx1 nCoV-19, a vaccine against Covid-19. Vaccine-induced immune thrombotic thrombocytopenia (VITT) with severe outcome is characterized by venous thrombosis, predominantly in cerebral veins, thrombocytopenia and anti-PF4/polyanion antibodies. Prolonged headaches and cutaneous hemorrhages, frequently observed after the ChAdOx1 ...